Entries Tagged 'From ScienceDaily: Biotechnology News' ↓

Cell biology: How ribosomes override their blockades

Ribosomes are “protein factories” in the cells of all living things. They produce proteins based on existing genetic codes stored on special nucleic acid molecules. These molecules, also called messenger RNA (mRNA) due to the genetic information encoded on them, are read by ribosomes in a stepwise manner. Defined start and stop signals on the mRNA direct this process. If a stop signal is missing, protein formation cannot be completed and the ribosome’s mode of operation is blocked.

DNA replication protein also has a role in mitosis, cancer

Scientists have discovered that a protein known as Cdt1, which is required for DNA replication, also plays an important role in a later step of the cell cycle, mitosis. The finding presents a possible explanation for why so many cancers possess not just genomic instability, but also more or less than the usual 46 DNA-containing chromosomes.

Scientists find differences in naked mole rat’s protein disposers

The naked mole rat's unusually long and healthy life span may be explained by cellular machinery that disposes of damaged proteins. Scientists found that this machinery differs in composition from that of other rodents.

Successful stem cell differentiation requires DNA compaction, study finds

New research findings show that embryonic stem cells unable to fully compact the DNA inside them cannot complete their primary task: Differentiation into specific cell types that give rise to the various types of tissues and structures in the body.

‘Switch’ to boost anti-viral response to fight infectious diseases

Scientists have for the first time, identified the molecular 'switch' that directly triggers the body's first line of defense against pathogens, more accurately known as the body's "innate immunity."

Scientists identify protein that stimulates brown fat to burn calories

Scientists have identified a protein which regulates the activation of brown fat in both the brain and the body's tissues.

Novel RNA transport mechanism: Ribonucleoprotein granules exit the nucleus via a budding mechanism

The movement of genetic materials, such as RNA and ribosomes, from the nucleus to the cytoplasm is a critical component in a cell's ability to make the proteins necessary for essential biological functions. Until now, it was believed the nuclear pore complex was the sole pathway between the cell nucleus and cytoplasm for these materials. New evidence reveals a novel budding mechanism, similar to the process used by some viruses, capable of exporting large ribonucleoprotein particles from the nucleus to the cytoplasm.

Enzyme corrects more than one million faults in DNA replication

Scientists have discovered that one enzyme corrects more than one million faults in DNA replication. And, it corrects the most common mistake in mammalian DNA.

Light used to switch on gene expression

Imagine being able to control genetic expression by flipping a light switch. Researchers are using light-activated molecules to turn gene expression on and off. Their method enables greater precision when studying gene function, and could lead to targeted therapies for diseases like cancer.

Regenerative medicine: Could the ways animals regenerate hair and feathers help restore human fingers and toes?

A review article that examines what's known about regenerative biology and applies it to regenerative medicine. Perhaps this knowledge could one day be used to regrow lost body parts.